Neuron-Binding Human Monoclonal Antibodies Support Central Nervous System Neurite Extension
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چکیده
منابع مشابه
Neuron-binding human monoclonal antibodies support central nervous system neurite extension.
Two human IgMs (sHIgM12 and sHIgM42) were identified that supported in vitro central nervous system (CNS) neurite extension equal to the potent neurite stimulatory molecule laminin. Both IgMs bound to multiple cell types in unfixed CNS tissue and to the surface of neurons in culture. Both monoclonal antibodies (mAbs) overrode the inhibitory effect of CNS mouse myelin on granule cell neurite ext...
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ژورنال
عنوان ژورنال: Journal of Neuropathology & Experimental Neurology
سال: 2004
ISSN: 0022-3069,1554-6578
DOI: 10.1093/jnen/63.5.461